Innovating the Future of TIDES with Over 20 Years of Expertise

For more than two decades, Sinopep has been a pioneer in the development and manufacturing of TIDES — a class of molecules central to the future of medicine. Innovation isn’t just a goal at Sinopep; it’s embedded in everything we do. With deep scientific expertise, a commitment to advanced technologies, and a forward-thinking mindset, we’ve earned recognition as a trusted leader in the global TIDES industry.

Our dedication to progress is exemplified in our newest achievement — the Fourth-Generation Large-Scale Peptide Production Facility, Workshop 601, located at our Lianyungang site. This state-of-the-art facility showcases the next generation of sustainable, automated, and intelligently controlled large-scale peptide manufacturing.

Workshop 601: A New Benchmark in Peptide Manufacturing:

• Large-Scale Automation for consistent, high-throughput peptide synthesis
• Central Control Room for optimized operational efficiency
• Advanced DCS Automation ensuring precise process control
• Intelligent & Close-Control System to enhance safety and reduce variability
• OEB5-Level Protection minimizing risk of chemical exposure to operators

At Sinopep, we don’t just follow industry trends — we set them. As we continue to shape the future of TIDES technology, we also support the growth and success of our partners, our people, and the global biopharmaceutical industry.

At Sinopep, your work contributes directly to improving and saving lives around the world. As a trusted partner in the global pharmaceutical supply chain, we develop and manufacture critical ingredients for medicines that treat both widespread chronic illnesses and rare, life-threatening conditions.

Join a purpose-driven team committed to advancing global healthcare. Together, we are building a healthier future—one molecule at a time.

At Sinopep, we foster a close-knit, entrepreneurial environment where your ideas matter and your contributions make a real impact. We are a solution-oriented team that values initiative, innovation, and collaboration at every level of the organization.

Teamwork is at the heart of our culture, creating a supportive and inclusive atmosphere where every individual is encouraged to grow and succeed.

Your development is our priority. At Sinopep, you’ll find abundant opportunities to expand your skills, take on new challenges, and build a rewarding career in a company shaping the future of global healthcare.

Location: United States (Remote)
Job ID: 20182088

Position Overview

We are seeking a remote-based Business Development Manager or Senior Manager to help drive growth across key markets. This role requires a strategic thinker with a strong background in the life sciences and proven experience navigating the API sales cycle within the biopharmaceutical industry.

Key Responsibilities

• Drive revenue growth by identifying, developing, and managing business opportunities across global markets.
• Cultivate and maintain long-term relationships with both senior and technical stakeholders in life sciences organizations.
• Generate and follow up on new business leads through cold calls, emails, networking, and industry referrals.
• Prepare and deliver impactful technical and commercial presentations tailored to client needs.
• Collaborate closely with internal project management and technical teams to ensure smooth execution and client satisfaction.
• Work with the marketing team to support market segmentation and share insights on customer needs, competitors, and industry trends.
• Represent Sinopep at relevant conferences, trade shows, and industry events to promote our capabilities and expand our network.

Qualifications

• BS, MS, or Ph.D. in Biology, Chemistry, or a related field in the life or physical sciences.
• Experience with CGMP API sales and/or production strongly preferred.
• Proven success in business development or sales in the biotech/pharma industry.
• Excellent written, verbal, and presentation communication skills.
• Energetic, outgoing, and self-motivated team player with strong organizational abilities.
• Enjoys scientific discussions, strategic planning, and relationship building.
• Fluent in English; additional languages are a plus.
• Familiarity with peptide chemistry or the broader TIDES landscape is advantageous.

Why Join Sinopep?

• Be part of a fast-growing, innovation-driven global CDMO leader in peptides and oligonucleotides.
• Work remotely with flexibility while engaging in meaningful business development initiatives.
• Collaborate with a high-performance team committed to scientific excellence and customer success.
• Competitive compensation, global exposure, and career advancement opportunities.

About Sinopep

Sinopep is a globally recognized and leading CDMO specializing in the production of synthetic peptides and oligonucleotides (TIDES). We partner with top-tier biotech and pharmaceutical companies to bring life-changing therapeutics and diagnostics to market. With one of the largest and most advanced peptide manufacturing facilities in the world, our operations have successfully passed multiple FDA, MFDS, and ANVISA inspections, as well as audits from leading global pharma organizations.

As we continue to expand, we are looking for driven, self-motivated professionals who want to contribute directly to our continued growth and leadership in the TIDES sector.

Join Sinopep—where science meets scale, and your work makes a global impact.
Apply now and help shape the future of therapeutic development worldwide.

Location: Hangzhou , Zhejiang , China

About Us

Sinopep is a leading China-based CDMO partner focused on accelerating the discovery, development, and manufacturing of innovative oligonucleotide therapeutics. We provide integrated solutions from preclinical to commercial supply, leveraging state-of-the-art facilities and deep scientific expertise. Join our dynamic team and contribute to advancing the next generation of genetic medicines for global partners.

Position Summary

We are seeking a highly motivated and creative PhD Scientist to join our expanding Oligonucleotide Process R&D team. This role is pivotal in designing, developing, optimizing, and scaling robust, cost-effective, and sustainable chemical processes for the synthesis and purification of therapeutic oligonucleotides (ASOs, siRNA, aptamers, etc.) for our global CDMO clients. The successful candidate will lead projects from early-stage feasibility through process characterization and technology transfer to GMP manufacturing.

Key Responsibilities

1. Lead Oligonucleotide Process Development: Design, plan, execute, and analyze experiments to develop and optimize solid-phase (SPOS) and/or solution-phase synthesis processes for complex oligonucleotides (including modified nucleotides, conjugates).
2. Purification & Analytical Focus: Develop, optimize, and scale chromatographic purification strategies (e.g., RP-HPLC, IE-HPLC, AEX) for crude oligonucleotides. Integrate analytical methods (HPLC, UPLC, MS, CE, UV, NMR) for process monitoring, impurity characterization, and control strategy development.
3. Scale-Up & Technology Transfer: Lead the scale-up of developed processes from laboratory to pilot plant and ultimately to GMP manufacturing scales. Author robust technical transfer documents and provide hands-on support during transfer activities.
4. Process Characterization & Validation:Contribute to or lead process characterization studies (e.g., identification of Critical Process Parameters – CPPs) to establish proven acceptable ranges (PARs) and support process validation (PPQ) activities.
5. Innovation & Problem Solving: Proactively identify process bottlenecks, inefficiencies, or quality issues and develop innovative, scientifically sound solutions. Explore novel technologies and methodologies to enhance synthesis, purification, or analytical capabilities.
6. Data Analysis & Documentation: Rigorously analyze experimental data, draw sound scientific conclusions, and maintain accurate, detailed laboratory notebooks and electronic records. Prepare high-quality technical reports, development reports, and sections of regulatory submissions (e.g., CMC modules).
7. Cross-Functional Collaboration: Work effectively with Analytical Development, Manufacturing, Project Management, Quality Assurance (QA), and Quality Control (QC) teams to ensure seamless project execution and alignment with client timelines and quality standards.
8. External Communication:Present scientific results clearly and concisely to internal stakeholders and external clients. Participate in technical discussions and project meetings.
9. Mentorship (Potential):Provide technical guidance and mentorship to junior scientists and research associates.

Required Qualifications & Experience

1. Education: PhD in Organic Chemistry, Medicinal Chemistry, Biochemistry, Chemical Engineering, or a closely related field.
2. Experience: 0-5 years of relevant industrial experience (post-PhD) in oligonucleotide process R&D within a pharmaceutical, biotech, or CDMO setting. Exceptional new PhD graduates with a strong focus on oligonucleotide synthesis/chemistry will be considered.
3. Core Technical Expertise:

• Deep understanding of oligonucleotide chemistry (phosphoramidite synthesis, protecting groups, coupling efficiency, side reactions).
• Proven hands-on experience in developing and optimizing oligonucleotide synthesis processes (SPOS required; solution-phase a plus).
• Extensive experience with oligonucleotide purification techniques, particularly preparative HPLC (RP, IE, AEX).
• Strong proficiency in analytical techniques for oligonucleotide characterization (HPLC/UPLC, MS, CE, UV-Vis, NMR interpretation).
• Experience with process optimization, troubleshooting, and scale-up principles.

How to Apply

Interested candidates should submit their CV/resume, a cover letter detailing their relevant experience and research interests to zhizhong.zhang@sinopep.com