Capacity

Commercial-Scale Manufacturing Capacity

With an established expertise in the synthetic manufacturing of complex large molecules, including peptides and oligonucleotides, we provide customized, science-driven solutions to advance your biologic development from early-stage research to commercial-scale production.

GMP Manufacturing Equipment

Large-scale reactors enable peptide and oligonucleotide production at multi-kilogram to ton quantities in a single campaign, dramatically improving cost-efficiency and supply reliability compared to small-vessel synthesis. High-capacity reversed-phase chromatography columns, often combined with dynamic axial compression, deliver superior resolution and loading capacity, allowing high-purity isolation of full-length product while removing truncated or deletion sequences in fewer cycles. These sys

maximize batch yield through optimized reaction conditions and loading strategies, reduce overall processing time with faster flow rates and shorter cycle times, and minimize risk by relying on proven, linear scale-up pathways that eliminate surprises during commercial transfer. The result is accelerated timelines, lower cost of goods, and consistent delivery of clinical and commercial material without costly re-optimization or delays.

Automated Synthesizers

Capacity	#Reactors	Total (L)
300L	2	600
500L	1	500
1000L	2	2,000
1200L	3	3,600
2000L	8	16,000
3000L	14	42,000

Dynamic axial compression (DAC) maintains uniform bed density throughout operation, delivering consistently high column efficiency, excellent peak symmetry, and long-term stability without the need for frequent repacking. It virtually eliminates channeling and voids even at large diameters, enabling reliable scale-up from grams to multi-ton production with predictable performance.

Purification Columns

DAC Columns	Brand	#
DAC 200 mm	Novasep	2
DAC 300 mm	Novasep	2
DAC 450 mm	Novasep	2
DAC 590 mm	Novasep	6
DAC 1000 mm	Novasep	3
DAC 200 mm	Hanbon	2
DAC 300 mm	Hanbon	8
DAC 600 mm	Hanbon	11
DAC 1000 mm	Hanbon	23
DAC 1200 mm	Hanbon	16

Lianyungang Site

GMP Peptides | Oligonucleotides | Small Molecules

1000+
Chemical Capacity (MT)

59.8
Total Site Area (acres)

7+
Peptide Capacity (MT)

1200+
Employees at this Location

3
Modalities Manufactured

Peptide Manufacturing Capacity

Flexible Scale-Up: From milligrams to hundreds of kilograms, our modular manufacturing systems support your program at every stage—from discovery to commercialization.

Peptide capacity (Q2): 6.16 tons
Projected capacity (Q4): 20–30 tons
Reactor sizes: 50–3000L
DAC purification columns: Up to 1,200 mm diameter
Spray dryer throughput: 32 kg/h (200+ kg per batch)

Zhejiang Jiande Site

Chemicals | Small Molecule APIs

10,000
Largest Reactors (L)

432
Number of Reactors (#)

650+
Number of Employees

24
Total Site Area (acres)

12
Synthetic Workshops

Inspection History

Since 2014, Sinopep’s GMP manufacturing facilities have successfully passed four (4) inspections conducted by the U.S. FDA, demonstrating our strong commitment to global regulatory compliance and product quality. In addition to these FDA audits, Sinopep has also undergone inspections by the Korean MFDS and has successfully completed 20 regulatory audits conducted by the NMPA in China.

Date	Inspected Product	Inspection Type	Result
Apr 2014	Peptide API	FDA CCMP	Pass
Apr 2016	Peptide API	FDA CCMP	Pass
Jan 2019	Routine Inspection	FDA CCMP	Pass
Nov 2023	Small Molecule & Peptide API	MFDS CCMP	Pass
Sep 2024	Routine Inspection (Unannounced Inspection)	FDA CGMP	Pass
July 2025	Semaglutide & Liraglutide	ANVISA CGMP	Pass